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Dog Pain Killer

"Dog pain killer can take the form of a NSAID, Opioid or natural remedy. Options include oral, topical or analgesics administered directly into the body. Never give your dog any drug unless it is with the advice of a veterinarian."




There are several categories of canine pain medications:

Conventional Analgesics should be an acceptable choice for managing pain and inflammation.

* NSAIDs
* Opioids
* Topical Dog Pain Killer

Unconventional Analgesics are medications designed for other purposes that are effective at relieving pain. There are two types:

1. Adjunctive analgesics which help to supplement the pain and inflammation relieving properties of other drugs.
2. Adjuvant analgesics are drugs that are prescribed to improve the way other drugs work.

Examples include:

* Tranquilizers (phenothiazines, benzodiazepines): this approach relaxes the muscles, reduces anxiety and fear and is used with other analgesics.

* N-methyl-D-aspartate (NMDA): this drug works by blocking sensitization in the spinal cord. It helps protect against a syndrome called "wind-up" where an earlier injury has a lingering effect in your dog, even if the pain has passed. If your dog has the expectation of pain they will still react like they are still experiencing the pain. It could take several hours for the effect to go away.

* Anticonvulsants: An example is the drug Gabapentin which may help reduce pain and central sensitization in chronic pain patients.

* Corticosteroids (prednisolone) is a strong antiinflammatory and immunosuppressive drug. It greatly reduces the feeling of pain.

* Tricyclic antidepressants (amitryptiline, imipramine) are effective analgesics for chronic pain, especially neuropathic or cancer-related pain.

Natural Remedies are just starting to be noticed by mainstream medicine for their ability to help with pain. Glucosamine in particular has been identified as a natural ingredient that can help restore cartilage in dogs suffering from some forms of arthritis. A good source to research is PetAlive Muscle & Joint Support Formula which is specifically formulated to treat Symptoms, relieve pain and reduce stiffness of arthritis, rheumatism and degenerative Joint Disease in dogs.

Nonsteroidal antiinflammatory agents (NSAIDs)

This is the most common type of dog pain killer. NSAIDs help to control inflammation and pain caused by some type of irritation or injury. Common symptoms include areas which are red in color, warm to the touch, are swollen or are visibly causing pain.

When treating dogs, NSAIDS are specifically used to help with problems associated with osteoarthritis and any pain after a dog undergoes surgery.

NSAIDs work by blocking the production of prostaglandins, the body chemicals that cause inflammation. Prostaglandin is known as a COX enzyme. There are three types of COX enzymes...1, 2, and 3. While in the past it wasn't known how NSAIDs work, it is now known that these drugs inhibit or stop the transmission of COX and that NSAIDs can be manufactured that target 1, 2 or 3 vs. all at once so each type of NSAID may have a different effect on your dog. Because of this it pays to experiment in two week trials with different drugs to understand which works best (it isn't clearly known how each medication will work in your specific dog and breed).

Although NSAID side effects are usually mild, if your dog is taking NSAIDs he or she needs to be monitored since this class of drugs is associated with problems such as:

* Gastrointestinal ulcers
* Intestinal bleeding
* Gastrointestinal perforations
* Liver problems (toxicity)
* Kidney problems (toxicity)
* Refusal to eat or eating less
* Behavioral Change (depression)* Vomiting
* Diarrhea
* Black tarry-colored stool
* Yellowing of gums
* Yellowing of skin
* Changes on the surface of the skin (scabs, redness, scratching)
* Change in the whites of the eyes
* Change in drinking
Changes in skin (scabs, redness, or scratching)

Caution should be taken with dogs that are taking diuretics (helps dogs increase their amount of urine) or have kidney, heart of liver problems. Don’t assume a NSAID for one dog is safe to give to another dog. Never give aspirin or corticosteroids along with a NSAID to your dog.

Brands and Types of NSAIDs for Dogs

* Etogesic (etodolac)
* Rimadyl (carprofen)
* Metacam (meloxicam)
* Deramaxx (deracoxib)
* Previcox(firocoxib)
* Zubrin (tepoxalin)
* Novox (carprofen)

Aspirin is also a NSAID. You should only give your dog medications if under the advice of a veterinarian since overdoses could have symptoms such as bleeding.

Opiods as a Dog Pain Killer

Opioids are a class of drugs that are used in hospitals for severe pain. This type of drug is popular among veterinarians because it is safe and if side effects are seen it can be quickly reversed. Side effects from these drugs include:

* vomiting
* constipation
* excitement
* respiratory issues
* depression
* slow heart beat (bradycardia)
* panting

These drugs are not for dogs with kidney or liver disease.

Morphine is the most common opioid. The drug is used to sedate your dog and to relieve pain. Side effects of morphine in addition to the ones listed include low blood pressure (hypotension).

Pentanyl citrate is another opioid which is considered a very strong drug. It is used as part of a patch on the skin for extended periods such as 3 days. It can take from 12 to 24 hours for the drug to be absorbed and effective.

Buprenorphine (Buprenex®) is an opioid that lasts longer than morphine. It is used when an analgesic is need for a 6 hour period.

Butorphanol Tartrate (Torbugesic®). is used in patients experiencing mild to moderate pain. It is administered either orally or can be injected. It lasts from 2 hours as a sedative or provides 40 minutes of pain relief.

Naloxone Hydrochloride can be quickly reversed if side effects are seen (in as little as 2 minutes). Positive effects on pain can last for 1 to 4 hours.

Tramadol is effective at controlling moderate to severe pain. It is administered orally and is commonly used after surgery to relieve pain. It is also used to treat pain from cancer and orthopedics.

Topical Dog Pain Killer

Topical analgesics are applied directly to the skin in the form of an ointment or cream. These types of dog pain killer products are used when your dog is suffering from:

* surface skin wounds
* skin punctures
* nose problems
* urinary catheterization

These products include ingredients such as lidocaine, Bupivacaine, tetracaine, and epinephrine. You can also use gauze pads with the medication that can be applied directly to the skin as a dog pain killer. The topical analgesic usually needs to be on the skin 20 to 30 minutes to be effective.

Constant Rate Infusions

A dog pain killer can also come into a form that is directly infused into your dog (CRI or constant rate infusion).

Types of CRI are:

Constant Infusion Opiods for Dog Pain

Morphine: this drug can be given as a dose or with a CRI approach. The advantage of CRI is that the dosing is even vs. high and low as the drug wears off. Morphine is used with dogs that are in severe pain.

Fentanyl: this is an opioid like Morphine. It works faster and wears off faster, but is more expensive.

Local Anesthetic

Lidocaine is a local anesthetic that is a safe analgesic for dogs, particularly those that suffer from any gastrointestinal problems. Side effects include muscle tremors, seizures, nausea or vomiting.

N-methyl-D-aspartate antagonists

Ketamine works to help with high levels of surgical pain by changing the way the spinal cord transmits pain. Ketamine is always be given in combination with an opioid.

Alpha2agonists

Recently alpha2agonists (Domitor®) helps dogs that have significant levels of stress or have an extended recovery period.

Have a Dog Pain or Medication related Question For Our Editors or A Story to Tell About This Topic?

Do you have a dog pain or medication related question for our editors or a helpful story to share? Please include information such as age, sex, breed, medical history, symptoms, diet, changes in behavior and medications.

We will do our best to get back to you quickly (depends on how many questions we receive each day). If you do require an immediate response we suggest using this online dog veterinary service that is available now.

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Sources for Dog Pain Killer

Managing Pain in Dogs
Dunn, T. J. DVM

Pain Control in Dogs and Cats
Hines, Ron DVM

Practical Pain Management - Part 1 and 2
N. Shaffran
Pfizer Animal Health, Erwinna, PA, USA



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